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OSTEON III

Osteon III is a synthetic osteoconductive bone graft material with excellent wettability, easy manipulation and a highly interconnected porous structure (micro- and macro-pores, approx. 80% porosity) facilitating new bone formation. Osteon III, as a synthetic bone graft material, eliminates any risk of disease transmission. Its composition makes it suitable for applications where bone grafting is desired for long term volume maintenance, such as ridge augmentation, sinus lift, cystic cavities, etc., due to its high content of HA (60%)

Effective Osteo-conductive Matrix for Bone Formation

100% synthetic bone graft material: HA (60%) + β-TCP (40%)

Applications
Periodontal Defect
Ridge Augmentation
Extraction Site
Cystic Cavities
Sinus Lift

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Technical Information

Vial Type

Syringe Type

1.Sinus
2.Lift

Osteon II: Overview

• Space maintenance
• Easy handling
• Excellent wettability
• Osteoconductive synthetic bone graft
• Pore Size : 200~400㎛
• Porosity: 80%

Osteon II: Applications

• Periodontal defect
• Ridge augmentation
• Extraction site
• Cystic cavities
• Sinus Lift & Osteotomy

Osteon III case courtesy of Dr. Root (Immediate Implantation)

01: NRLine Implant placement.
02: Osteon III
03: 3 months 2 weeks / 2nd surgery.
04: Final restoration.
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Citation

Simultaneous lateral bone augmentation and implant placement using a particulated synthetic bone substitute around chronic peri-implant dehiscence defects in dogs

Ui-Won Jung, Jae-Kook Cha, Fabio Vignoletti, Javier Nuñez, Javier Sanz, Mariano Sanz

(J Clin Periodontol. 2017 Nov;44(11):1172-1180. doi: 10.1111/jcpe.12802. Epub 2017 Sep 21)

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A Comparative Study with Biphasic Calcium Phosphate to Deproteinized Bovine Bone in Maxillary Sinus Augmentation: A Prospective Randomized and Controlled Clinical Trial

Ji-Su Oh, Yo-Seob Seo, Gyeong-Je Lee, Jae-Seek You, Su-Gwan Kim

(Int J Oral Maxillofac Implants. January/February 2019;34(1):233–242. doi: 10.11607/jomi.7116. Epub 2018 Dec 5)

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Comparison of Three Biphasic Calcium Phosphate Block Substitutes: A Histologic and Histomorphometric Analysis in the Dog Mandible

Octavi Ortiz-Puigpelat, Basel Elnayef, Marta Satorres-Nieto, Jordi Gargallo-Albiol, Federico Hernández-Alfaro

(Int J Periodontics Restorative Dent. May/Jun 2019;39(3):315-323. doi: 10.11607/prd.3837)

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Evaluation of different combinations of Biphasic calcium phosphate and growth factors for bone formation in calvarial defects in a rabbit model

Sung-Min Chung, In Kwon Jung, Byung-Ho Yoon, Bok Ryul Choi, David M Kim, Jung Sun Jang

(Int J Periodontics Restorative Dent. 2016;36 Suppl:s49-59. doi: 10.11607/prd.2633.)

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The clinical and radiographic outcomes of Schneiderian membrane perforation without repair in sinus elevation surgery

Won-Bae Park, Ji-Young Han, Philip Kang, Fatemeh Momen-Heravi

(Clin Implant Dent Relat Res. 2019 Oct;21(5):931-937. doi: 10.1111/cid.12752. Epub 2019 Apr 4.)

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OSTEON II

Osteon II is a synthetic osteoconductive bone graft material with higher content of β-TCP compared to Osteon III. It possesses interconnected porous (micro and macro-pores, approx. 70% porosity) structure similar to that of cancellous bone. Osteon II as, a synthetic bone graft material eliminates any risk of disease transmission. Its composition makes it suitable where new bone formation is desired, such as extraction socket preservation, periodontal defects, and etc., due to its high content of β-TCP (70%)

Effective Osteo-conductive Matrix for Bone Formation

100% synthetic bone graft material: HA (30%) + β-TCP (70%)

Applications
Extraction Site
Ridge Augmentation
Cystic Cavities
Sinus Lift Periodontal Defect

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Arrow Icon Green
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Technical Information

Vial Type

Syringe Type

1.Sinus
2.Lift

Osteon II: Overview

• Highly resorbable due to higher β-TCP content
• Easy handling
• Excellent wettability
• Osteoconductive synthetic bone graft
• Pore Size : 250㎛
• Porosity : 70%

Osteon II: Applications

• Extraction site grafting
• Ridge augmentation
• Cystic cavities
• Sinus lift & osteotomy
• Periodontal defect

Osteon II + 3 case courtesy of Dr. SM Han (Sinus Lifting)

01: Bone defect.
02: Osteon II
03: Osteon II + Collagen Membrane.
04: After 5 months follow up.
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Citation

Alveolar ridge reconstruction with a composite alloplastic biomaterial

David M Kim, Marcelo Camelo, Myron Nevins, Ardavan Fateh, Peter Schupbach, Marc Nevins

(Int J Periodontics Restorative Dent. 2012 Dec;32(6):e204-9)

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Ridge Preservation With and Without Primary Wound Closure: A Case Series

David M Kim, Nicola De Angelis, Marcelo Camelo, Marc L Nevins, Peter Schupbach, Myron Nevins

(Int J Periodontics Restorative Dent. Jan-Feb 2013;33(1):71-8. doi: 10.11607/prd.1463)

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The Clinical and Histologic Outcome of Dental Implant in Large Ridge Defect Regenerated With Alloplast: A Randomized Controlled Preclinical Trial

David M Kim, Marc L Nevins, Zhao Lin, Ardavan Fateh, Soo-Woo Kim, Peter Schupbach, Myron Nevins

(J Oral Implantol. 2013 Apr;39(2):148-53. doi: 10.1563/AAID-JOI-D-12-00242)

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A Prospective, Randomized Controlled Preclinical Trial to Evaluate Different Formulations of Biphasic Calcium Phosphate in Combination With a Hydroxyapatite Collagen Membrane to Reconstruct Deficient Alveolar Ridges

David M Kim, Marc L Nevins, Zhao Lin, Ardavan Fateh, Soo-Woo Kim, Peter Schupbach, Myron Nevins

(J Oral Implantol. 2013 Apr;39(2):148-53. doi: 10.1563/AAID-JOI-D-12-00242)

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Effect of different hydroxyapatite:β-Tricalcium Phosphate ratios on the osteoconductivity of Diphasic Calcium Phosphate in the rabbit sinus model

Hyun-Chang Lim, Ming-Lan Zhang, Jung-Seok Lee, Ui-Won Jung, Seong-Ho Choi

(Int J Oral Maxillofac Implants. Jan-Feb 2015;30(1):65-72. doi: 10.11607/jomi.3709. Epub 2014 Sep 26)

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Biphasic hydroxyapatite and β-tricalcium phosphate biomaterial behavior in a case series of maxillary sinus augmentation in humans

Allinson Olaechea, Gerardo Mendoza-Azpur, Francisco O Valle, Miguel Padial-Molina, Natividad Martin-Morales, Pablo Galindo-Moreno

(Clin Oral Implants Res. 2019 Apr;30(4):336-343. doi: 10.1111/clr.13419. Epub 2019 Mar 24)

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Collagen Membrane

Dentium Collagen Membrane is a resorbable and multi-layered thin barrier membrane designed for a guided bone/tissue regeneration procedure. It is made by crosslinking of pure collagen type I derived from bovine tendon. It features:

A slow resorption rate over 6 months, long lasting barrier function for stabilizing bone graft materials and supporting bone growth by space maintenance

Easy manipulation with excellent wettability

Dual sided use

Slow Resorption (> 6 months) and Volume Maintenance

Biodegradable barrier membrane for guided bone / tissue regeneration

Applications
Periodontal / Intra-bony Defect
Ridge Augmentation
Extraction Socket Grafting
Guided Bone Regeneration Sinus Lift

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Technical Information

Osteon II: Overview

• Pure Type 1 Collagen derived from New Zealand bovine tendon.
• Thin membrane (300µm) with multiple layers for easy manipulation and good mechanical strength in surgery.
• Resorption period provides enough time for stabilizing graft materials and supporting bone growth.
• Dual-sided usage.

Osteon II: Applications

• Periodontal / Intrabony Defects.
• Ridge Augmentation.
• Extraction Socket Grafting.
• Guided Bone Regeneration (GBR).
• Sinus lift

Collagen Membrane case courtesy of Dr. W.B. Park (3-wall defect case)

01: Pre-Op
02: GBR (Osteon III)
03: GBR (Collagen Membrane)
04: 2nd Surgery
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Citation

Physicochemical characterization of barrier membranes for bone regeneration

Jordi Caballé-Serrano, Antonio Munar-Frau, Luis Delgado, Roman Pérez, Federico Hernández-Alfaro

(J Mech Behav Biomed Mater. 2019 Sep;97:13-20.
doi: 10.1016/j.jmbbm.2019.04.053. Epub 2019 May 4.)

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A Comparative Study with Biphasic Calcium Phosphate to Deproteinized Bovine Bone in Maxillary Sinus Augmentation: A Prospective Randomized and Controlled Clinical Trial

Ji-Su Oh, Yo-Seob Seo, Gyeong-Je Lee, Jae-Seek You, Su-Gwan Kim

(Int J Oral Maxillofac Implants. January/February 2019;34(1):233–242. doi: 10.11607/jomi.7116. Epub 2018 Dec 5)

Read Article

Comparison of Three Biphasic Calcium Phosphate Block Substitutes: A Histologic and Histomorphometric Analysis in the Dog Mandible

Octavi Ortiz-Puigpelat, Basel Elnayef, Marta Satorres-Nieto, Jordi Gargallo-Albiol, Federico Hernández-Alfaro

(Int J Periodontics Restorative Dent. May/Jun 2019;39(3):315-323. doi: 10.11607/prd.3837)

Read Article